２０２１年

2021年 業績

  1. Miyamoto M, Tsuboi R, Harada K, Cho O, Sugita T: Skin microbiome of patients with interdigital tinea pedis: Corynebacterium striatum is more abundant in the patients. J Dermatol 48: 1106-1108, 2021.
  2. Tsuboi R, Mochizuki T, Ito H, Kawano S, Suzuki Y, Naka W, Hata Y, Hamaguchi T, Maruyama R: Validation of a lateral flow immunochromatographic assay for tinea unguium diagnosis. J Dermatol 48: 633–637, 2021.
  3. Watanabe S, Iozumi K, Abe M, Ito Y, Uesugi T, Onoduka T, Kato I, Kato F, Kodama K, Takahashi H, Takeda O, Tomizawa K, Tateishi Y, Fujii M, Mayama J, Muramoto F, Yasuda H, Yamanaka K, Oh-I T, Kasai H, Tsuboi R, Hattori N, Maruyama R, Omi T, Shimoyama H, Nakasu I, Watanabe-Okada E, Nishimoto S, Mochizuki T, Fukuzawa M, Seishima M, Sugiura K, Yamamoto O, Shindo M, Kiryu H, Kusuhara M, Takenaka M: Clinical effectiveness of efinaconazole 10% solution for treatment of onychomycosis with longitudinal spikes. J Dermatol 48 : 1474-1481, 2021.
  4. Kano R, Noguchi H, Harada K, Hiruma M: Rapid Molecular Detection of Terbinafine-resistant Dermatophytes. Med Mycol J 62 : 41-44, 2021.
  5. Morita A, Takahashi H, Ozawa K, Imafuku S, Takekuni N, Takahashi K, Matsuyama T, Okubo Y, Zhao Y, Kitamura S, Takei K, Yokoyama M, Hayashi N, Terui T: Long-term analysis of adalimumab in Japanese patients with moderate to severe hidradenitis suppurativa: Open-label phase 3 results. J Dermatol 48 : 3-13, 2021.
  6. Imafuku S, Nemoto O, Okubo Y, Komine M, Schafer P, Petric R, Ohtsuki M: Pharmacodynamic analysis of apremilast in Japanese patients with moderate to severe psoriasis: Results from a phase 2b randomized trial. J Dermatol 48 : 80-84, 2021.
  7. Serizawa N, Okazaki S, Otsuka Y, Koto M, Okabe K, Ito M, Morita T, Hoashi T, Saeki H, Abe N, Mori M, Okubo Y, Yano Y, Mitsui H, Kanda N: Dietary habits in Japanese patients with palmoplantar pustulosis. J Dermatol 48: 366-375, 2021.
  8. Imafuku S, Kanai Y, Murotani K, Nomura T, Ito K, Ohata C, Yamazaki F, Miyagi T, Takahashi H, Okubo Y, Saeki H, Honma M, Tada Y, Mabuchi T, Higashiyama M, Kobayashi S, Hashimoto Y, Seishima M, Kakuma T: Utility of the Dermatology Life Quality Index at initiation or switching of biologics in real-life Japanese patients with plaque psoriasis: Results from the ProLOGUE study. J Dermatol Sci 101: 185-193, 2021.
  9. Reich K, Papp KA, Blauvelt A, Langley RG, Armstrong A, Warren RB, Gordon KB, Merola JF, Okubo Y, Madden C, Wang M, Cioffi C, Vanvoorden V, Lebwohl M: Bimekizumab versus ustekinumab for the treatment of moderate to severe plaque psoriasis (BE VIVID): efficacy and safety from a 52-week, multicentre, double-blind, active comparator and placebo controlled phase 3 trial. Lancet 6;397(10273): 487-498, 2021. doi: 10.1016/S0140-6736(21)00125-2.
  10. Imafuku S, Nakagawa H, Igarashi A, Morita A, Okubo Y, Sano S, Tada Y, Nemoto O, Rozzo SJ, Kawamura M, Ohtsuki M: Long-term efficacy and safety of tildrakizumab in Japanese patients with moderate to severe plaque psoriasis: Results from a 5-year extension of a phase 3 study (reSURFACE 1). J Dermatol 48: 844-852, 2021.
  11. Igarashi A, Nakagawa H, Morita A, Okubo Y, Sano S, Imafuku S, Tada Y, Honma M, Mendelsohn AM, Kawamura M, Ohtsuki M: Efficacy and safety of tildrakizumab in Japanese patients with moderate to severe plaque psoriasis: Results from a 64-week phase 3 study (reSURFACE 1). J Dermatol 48: 853-863, 2021.
  12. Okubo Y, Torisu-Itakura H, Hanada T, Aranishi T, Inoue S, Ohtsuki M: Evaluation of treatment satisfaction misalignment between Japanese psoriasis patients and their physicians – Japanese psoriasis patients and their physicians do not share the same treatment satisfaction levels. Curr Med Res Opin 37: 1103-1109, 2021.
  13. Okubo Y, Tang AC, Inoue S, Torisu-Itakura H, Ohtsuki M: Comparison of Treatment Goals between Users of Biological and Non-Biological Therapies for Treatment of Psoriasis in Japan. J Clin Med 10: 5732, 2021.
  14. Okubo Y, Ohtsuki M, Komine M, Imafuku S, Kassir N, Petric R, Nemoto O: Population pharmacokinetic and exposure–response analysis of apremilast in Japanese subjects with moderate to severe psoriasis. J Dermatol 48: 1652-1664, 2021.
  15. Okubo Y, Morishima H, Zheng R, Terui T: Sustained efficacy and safety of guselkumab in patients with palmoplantar pustulosis through 1.5 years in a randomized phase 3 study. J Dermatol 48 : 1838-1853, 2021.
  16. Morita A, Kotowsky N, Gao R, Shimizu R, Okubo Y: Patient characteristics and burden of disease in Japanese patients with generalized pustular psoriasis: Results from the Medical Data Vision claims database. J Dermatol 48: 1463–1473, 2021.
  17. Okubo Y, Kotowsky N, Gao R, Saito K, Morita A: Clinical characteristics and health-care resource utilization in patients with generalized pustular psoriasis using real-world evidence from the Japanese Medical Data Center database. J Dermatol 48: 1675-1687, 2021.
  18. Bieber T, Simpson EL, Silverberg JI, Thaçi D, Paul C, Pink AE, Kataoka Y, Chu CY, DiBonaventura M, Rojo R, Antinew J, Ionita I, Sinclair R, Forman S, Zdybski J, Biswas P, Malhotra B, Zhang F, Valdez H; JADE COMPARE Investigators(Okubo Y (Collaborators)): Abrocitinib versus Placebo or Dupilumab for Atopic Dermatitis. N Engl J Med 384: 1101-1112, 2021.
  19. Nogita T, Nomura Y, Kurokawa I: Postinflammatory papule: A tentative new designation for acne vulgaris. Dermatol Ther (Heidelb) 11: 1867-1869, 2021.
  20. Ito T, Maeda T, Egusa C, Abe N, Seshimo H, Okubo Y, Harada K: Effectiveness of omalizumab in two cases of normocomplementemic urticarial vasculitis due to perivascular mast cell infiltration. Allergol Int 70 : 269-270, 2021.
  21. Irisawa R, Tsuboi R, Saito M, Harada K: Treatment of intra-anal warts with imiquimod 5% cream: A single-center prospective open study. J Dermatol 48 : 476-480, 2021.
  22. Mae K, Tsuboi R, Irisawa R, Sato T, Fukushima N, Harada K: Recent reductions in the size of facial pigmented basal cell carcinoma at diagnosis and the surgical margin: A retrospective and comparative study. J Dermatol 48 : 661–666, 2021.
  23. Wang Y, Matsushita K, Jackson J, Numata T, Zhang Y, Zhou G, Tsai M, Galli SJ: Transcriptome programming of IL-3-dependent bone marrow-derived cultured mast cells by stem cell factor (SCF). Allergy 76 : 2288-2291, 2021.
  24. Uchiyama M, Harada K, Tobita R, Irisawa R, Tsuboi R: Histopathologic and dermoscopic features of 42 cases of folliculitis decalvans: A case series. J Am Acad Dermatol 85 : 1185-1193, 2021.
  25. Hiruma J, Noguchi H, Hase M, Tokuhisa Y, Shimizu T, Ogawa T, Hiruma M, Harada K, Kano R: Epidemiological study of terbinafine-resistant dermatophytes isolated from Japanese patients. J Dermatol 48 : 564-567, 2021.
  26. Hiruma J, Harada K, Hirayama M, Egusa C, Tobita R, Masuda-Kuroki K, Abe N, Tsuboi R, Okubo Y: Blockade of the IL-17 signaling pathway increased susceptibility of psoriasis patients to superficial fungal infections. J Dermatol Sci 101 : 145-146, 2021.
  27. Mori M, Tobita R, Egusa C, Maeda T, Abe N, Kawakami H, Mae K, Matsumoto Y, Kawachi Y, Okubo Y: Clinical background of patients with psoriasiform skin lesions due to tumor necrosis factor antagonist administration at a single center. J Dermatol 48: 1745-1753, 2021.
  28. Takeda Y, Kawakami H, Mori M, Hiruma J, Fujimori K, Umefune R, Mae K, Saitou M, Harada K, Okubo Y: Case of generalized pustular psoriasis preceded by acute generalized pustular bacterid-like eruptions on the palms and soles. J Dermatol 48 : e250-e251, 2021.
  29. Seshimo H, Ito T, Egusa C, Numata T, Kobayashi T, Abe N, Niitsuma T, Okubo Y, Harada K: A case of anaphylactic shock induced by mealworm antigen in the bite of a Japanese flying squirrel. J Eur Acad Dermatol Venereol 35: e519-e520, 2021.
  30. Seshimo H, Ito T, Egusa C, Numata T, Kobayashi T, Abe N, Niitsuma T, Okubo Y, Harada K: Response to 'Reply to "A case of anaphylactic shock induced by mealworm antigen in the bite of a Japanese flying squirrel" by Seshimo et al.' by Schmid-Grendelmeier and Guillet. J Eur Acad Dermatol Venereol 35 : e618, 2021.
  31. Hayakawa K, Wakimoto H, Mae K, Irisawa R, Harada K: Efficacy and safety of full-dose dabrafenib and trametinib combination therapy in a patient on hemodialysis with metastatic melanoma. Int J Dermatol 60 : 516-517, 2021.
  32. 伊藤友章, 大久保ゆかり, 原田和俊: 慢性特発性蕁麻疹に対するオマリズマブ投与患者105例の検討. 日臨皮会誌 38 : 892-897, 2021.

皮膚科学分野について

皮膚科診療について

研究・業績